The authors describe how a team of researchers found a way to treat pain in felines with a synthetic version of a pain-relieving drug.
The research, published in the journal Science Translational Medicine, is the latest in a series of studies looking at the ability of synthetic opioids to alleviate pain.
The drug, named “X-Tramadol,” is the active ingredient in OxyContin.
The researchers tested X-Trams in lab animals that had been injected with OxyContin and then put in a virtual environment to receive injections.
One group of mice received a dose of OxyContin that contained a synthetic opioid called “XTC,” while another group received the placebo.
The synthetic opioid was the active one in both groups.
The research found that mice injected with XTC experienced increased pain levels for as long as two weeks.
After that, they reported significantly less pain, and less severe pain, for up to four weeks after the injection.
The synthetic opioids also caused mice to stop using OxyContin, but that was less dramatic than the effects of the injection itself.
The mice who had been given OxyContin also showed significantly less fear, anxiety and aggression.
Researchers said the findings suggest the opioid’s active ingredient could be used to treat a wide range of chronic pain conditions.
The researchers said the synthetic opioid could potentially be used as an adjunct to conventional analgesics, including ibuprofen, acetaminophen and acetaminoplastin. “
We hope this work will lead to more widespread and effective use of these synthetic opioids in the future.”
The researchers said the synthetic opioid could potentially be used as an adjunct to conventional analgesics, including ibuprofen, acetaminophen and acetaminoplastin.
They said it could also be used for other types of chronic illnesses, including multiple sclerosis, arthritis and osteoarthritis.
The work was funded by the National Institutes of Health.